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Anotácia knihy

A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs.Announcement of the complete sequencing of the human genome in April 2003 demonstrated the presence of thousands of targets for antisense oligonucleotides and opened the way to hundreds of preclinical animal studies and some 20 ongoing clinical trials. In this second edition of Antisense Therapeutics, a team of leading researchers and clinical scientists demonstrate the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs. §Highly practical and disease oriented, Antisense Therapeutics, Second Edition offers not only a primer for a new generation of drug discovery researchers, but also an illuminating exploration of the potential in exploiting RNA inhibition for novel human therapeutics.

Parametre knihy

Zaradenie knihy Knihy po anglicky Mathematics & science Biology, life sciences Cellular biology (cytology)

• Celý názov: Antisense Therapeutics
• Autor: M. Ian Phillips
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 344
• EAN: 9781617374210
• ISBN: 1617374210
• ID: 01432057
• Nakladateľ: Humana Press Inc.
• Hmotnosť: 501 g
• Rozmery: 229 × 152 × 19 mm
• Dátum vydania: 28. October 2010

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