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This volume presents state-of-the-art methods for reliable detection of epigenetic changes in the nervous system. Epigenetic Methods in Neuroscience Research guides readers through methods for the analyses of chromatin remodeling, transposable elements, non-coding RNAs, such as miRNAs, and circadian oscillations, including: analysis of DNA methylation in neuronal and glial cells or small tissue samples; sensitive method for quantification of alternative methylated forms of cytosines by liquid chromatography/mass spectrometry; affinity-based detection of modified cytosines by immunohistochemistry or methylated DNA immunoprecipitation; chromatin immunoprecipitation, or ChIP; miRNA high-throughput profiling and the in situ detection of miRNA subtle expression in the brain; analysis of genes with alternative 3'UTRs; and the cite-specific delivery of chromatin-modifying drugs. Written in the popular Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your own laboratory.§§Concise and easy-to-use, Epigenetic Methods in Neuroscience Research provides multidisciplinary epigenetic approach to study genome, and neural, plasticity that will help the reader to successfully address the challenges associated with neurodevelopmental, psychiatric, and neurodegenerative disorders.§§

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Zaradenie knihy Books in English Mathematics & science Biology, life sciences Life sciences: general issues

• Celý názov: Epigenetic Methods in Neuroscience Research
• Autor: Nina Karpova
• Jazyk: Angličtina
• Väzba: Pevná
• Počet strán: 258
• EAN: 9781493927531
• ISBN: 1493927531
• ID: 09249497
• Nakladateľ: Humana Press Inc.
• Hmotnosť: 796 g
• Rozmery: 189 × 263 × 16 mm
• Dátum vydania: 13. October 2015

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