Code: 07059056

Prostaglandin E1

Name: Prostaglandin E 1
Brand: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
SKU: 07059056
Price: 52.74 EUR
Availability: InStock
Author: H. Böhme
ISBN: 9783642739446

by H. Böhme, Heinz Heidrich, Waltraud Rogatti

Language: German
Binding: Paperback
Number of pages: 200
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, 2012
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Book synopsis

Dieses erste deutschsprachige Buch zum Thema der pharmakologischen und therapeutischen Wirksamkeit von Prostaglandin E1 enthält aktuelle zusammengefaßte Originalarbeiten. Neben den bekannten vasodilatierenden und die Thrombozytenfunktion hemmenden Eigenschaften werden eine Vielzahl weiterer Wirkmechanismen nachgewiesen, so der positive Einfluß auf die Pathogenese und Progression der Atherosklerose, die Aktivierung der endogenen Fibrinolyse, die Hemmung der Neutrophilen-Aktivierung und die Ökonomisierung des zellulären Stoffwechsels. Die Wirksamkeit von intraarteriell und intravenös appliziertem Prostaglandin E1 bei schwerer arterieller Verschlußkrankheit wird durch kontrollierte Studien an Patienten mit Claudicatio, Ruheschmerzen oder Nekrosen belegt sowie weitere Indikationen diskutiert.