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Opis

Following an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.§

Szczegóły książki

Kategoria Książki po angielsku Mathematics & science Biology, life sciences Zoology & animal sciences

• Pełny tytuł: Genes and Mechanisms in Vertebrate Sex Determination
• Autor: Gerd Scherer, Michael Schmid
• Język: Angielski
• Oprawa: Miękka
• Liczba stron: 205
• EAN: 9783034877831
• ISBN: 3034877838
• ID: 02116327
• Wydawca: Springer Basel
• Waga: 389 g
• Wymiary: 244 × 170 × 13 mm
• Data wydania: 03. March 2013

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