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Więcej informacji o TGF- Signaling

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Opis

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF- from the basic principles to the practical applications. Chapters provide basic introduction of TGF- signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF- signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.§§Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.§

Szczegóły książki

Kategoria Książki po angielsku Mathematics & science Biology, life sciences Cellular biology (cytology)

• Pełny tytuł: TGF- Signaling
• Podtytuł: Methods and Protocols
• Autor: Xin-Hua Feng, Pinglong Xu, Xiy Lin
• Język: Angielski
• Oprawa: Twarda
• Liczba stron: 394
• EAN: 9781493929658
• ISBN: 1493929658
• ID: 09300983
• Wydawca: Humana Press Inc.
• Waga: 9992 g
• Wymiary: 254 × 178 × 20 mm
• Data wydania: 05. November 2015

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