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Book synopsis

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS).
The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.

Book details

• Full title: AIDS Pathogenesis
• Author: H. Schuitemaker, Frank Miedema
• Language: English
• Binding: Paperback
• Number of pages: 300
• EAN: 9789401706865
• ID: 43424941
• Publisher: Springer Nature B.V.
• Weight: 425 g
• Dimensions: 234 × 156 mm
• Date of publishing: 14. March 2014

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