Code: 10901247

Complexo de Degradacao de b-Catenina e o Cancer de mama

Name: Complexo de Degradacao de b-Catenina e o Cancer de mama
Brand: Novas Edicoes Academicas
SKU: 10901247
Price: 83.78 EUR
Availability: InStock

by Aristizabal-Pachon Andres Felipe

Language: Portuguese
Binding: Paperback
Number of pages: 164
Publisher: Novas Edicoes Academicas, 2015
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O câncer de mama é a neoplasia responsável pelo maior número de mortes em mulheres no Brasil, portanto, é importante encontrar novos marcadores específicos e de diagnóstico precoce, utilizando procedimentos simples e rápidos. A via de sinalizaçăo Wnt regula importantes funçőes celulares como proliferaçăo, sobrevida e adesăo. Esta via está associada com os processos de iniciaçăo e progressăo em muitos tipos tumorais, como câncer de cólon familiar, melanoma e pulmăo; sendo que mutaçőes em ß-Catenina (CTNNb1) explicam só 30% dos casos de sinalizaçăo aberrante encontrada no câncer de mama, indicando que existem outros componentes e/ou reguladores da via que possam estar envolvidos.