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Book synopsis

This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.

Book details

Book category Books in English Mathematics & science Biology, life sciences Life sciences: general issues

• Full title: Computational Methods for Processing and Analysis of Biological Pathways
• Author: Anastasios Bezerianos, Andrei Dragomir, Panos Balomenos
• Language: English
• Binding: Paperback
• Number of pages: 87
• EAN: 9783319538679
• ISBN: 3319538675
• ID: 15789061
• Publisher: Springer International Publishing AG
• Weight: 182 g
• Dimensions: 158 × 239 × 8 mm
• Date of publishing: 08. June 2017

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