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Book synopsis

This book combines in a comprehensive manner the results of biochemical studies, structural biology investigations and small molecule design within some of the protein classes that play major roles in signal transduction: the protein kinases, the growth factor family and the transcription factors. It is described how these proteins communicate with each other via different signalling pathways. Three-dimensional structures of these proteins are presented, and their interaction with small molecules and co-factors are described. The use of these proteins for pharmaceutical research and the design of small molecules and their selectivity towards such proteins are discussed.

Book details

Book category Books in English Mathematics & science Biology, life sciences Biochemistry

• Full title: Data Mining in Structural Biology
• Subtitle: Signal Transduction and Beyond
• Author: I. Schlichting, U. Egner
• Language: English
• Binding: Paperback
• Number of pages: 209
• EAN: 9783662046470
• ISBN: 3662046474
• ID: 02646613
• Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Weight: 298 g
• Dimensions: 210 × 148 × 13 mm
• Date of publishing: 18. April 2014

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