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Book synopsis

This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.

Book details

Book category Books in English Medicine Medicine: general issues Medical equipment & techniques

• Full title: Design & Analysis of Sequential Clinical Trials 2e
• Author: John Whitehead
• Language: English
• Binding: Hardback
• Number of pages: 328
• EAN: 9780471975502
• ISBN: 0471975508
• ID: 04895204
• Publisher: John Wiley & Sons Inc
• Weight: 588 g
• Dimensions: 239 × 160 × 20 mm
• Date of publishing: 25. June 1997

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