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Book synopsis

One of the most challenging issues for clinical trial investigators, sponsors, and regulatory officials is the interpretation of experimental results that are composed of the results of multiple statistical analyses. These analyses may include the effect of therapy on multiple endpoints, the assessment of a subgroup analysis, and the evaluation of a dose-response relationship in complex mixtures. Multiple Analyses in Clinical Trials: Fundamentals for Clinical Investigators is an essentially nonmathematical discussion of the problems posed by the execution of multiple analyses in clinical trials. It concentrates on the rationale for the analyses, the difficulties posed by their interpretation, easily understood solutions, and useful problem sets. This text will help clinical investigators understand multiple analysis procedures and the key issues when designing their own work or reviewing the research of others. This book is written for advanced medical students, clinical investigators at all levels, research groups within the pharmaceutical industry, regulators at the local, state, and federal level, and biostatisticians. Only a basic background in health care and introductory statistics is required.

Book details

Book category Books in English Medicine Medicine: general issues Medical equipment & techniques

• Full title: Multiple Analyses in Clinical Trials
• Subtitle: Fundamentals for Investigators
• Author: Lemuel A. Moye
• Language: English
• Binding: Hardback
• Number of pages: 436
• EAN: 9780387007274
• ISBN: 038700727X
• ID: 01380716
• Publisher: Springer-Verlag New York Inc.
• Weight: 1820 g
• Dimensions: 235 × 155 × 27 mm
• Date of publishing: 30. July 2003

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