You might also like

More about Restriction Endonucleases

• Book details
• Synopsis
• Trending among others

You get 498 loyalty points

Book synopsis

Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.

Book details

Book category Books in English Mathematics & science Biology, life sciences Biochemistry

• Full title: Restriction Endonucleases
• Author: Alfred M. Pingoud
• Language: English
• Binding: Hardback
• Number of pages: 443
• EAN: 9783540205029
• ISBN: 3540205020
• ID: 01558792
• Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Weight: 956 g
• Dimensions: 235 × 155 × 33 mm
• Date of publishing: 19. February 2004

Trending among others

---

---

---