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Book synopsis

This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.

Book details

Book category Books in English Medicine Clinical & internal medicine Dermatology

• Full title: Systemic Sclerosis
• Subtitle: Basic and Translational Research
• Author: Kazuhiko Takehara, Manabu Fujimoto, Masataka Kuwana
• Language: English
• Binding: Hardback
• Number of pages: 247
• EAN: 9784431557074
• ISBN: 4431557075
• ID: 09341328
• Publisher: Springer Verlag, Japan
• Weight: 5552 g
• Dimensions: 235 × 155 × 242 mm
• Date of publishing: 24. December 2015

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