Code: 19185748

The CD38 molecule

Name: The CD38 molecule
Brand: LAP Lambert Academic Publishing
SKU: 19185748
Price: 25.87 EUR
Availability: InStock
Author: Ahlem Mokrane
ISBN: 9786138339779

by Ahlem Mokrane

Language: English
Binding: Paperback
Number of pages: 84
Publisher: LAP Lambert Academic Publishing, 2018
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25.87 €

RRP: 30.36 €

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Book synopsis

CD38 is a transmembrane glycoprotein type II, which is expressed on normal hematopoietic cells and in non-hematopoietic tissues. Notably, CD38 is highly expressed in multiple myeloma, chronic lymphocytic leukemia, and other diseases. CD38 plays several roles, including ectoenzyme, receptor, adhesion molecule, and is involved in signal transduction. The cytotoxic mechanisms of daratumumab, which is considered a new high affinity human therapeutic mAb against a single CD38 epitope. CD38 represents a promising target for mAb-based immunotherapy, which has already and will continue to transform the treatment landscape into diseases, including multiple myeloma.