Code: 01438662

Replicating Vaccines

Name: Replicating Vaccines
Brand: Birkhauser Verlag AG
SKU: 01438662
Price: 206.13 EUR
Availability: InStock
Author: Philip R. Dormitzer
ISBN: 9783034602761

by Philip R. Dormitzer, Christian W. Mandl, Rino Rappuoli

Language: English
Binding: Hardback
Number of pages: 447
Publisher: Birkhauser Verlag AG, 2010
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206.13 €

RRP: 223.27 €

You save 17.14 €

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Book synopsis

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines.§This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.