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Book synopsis

More than 7 billion people inhabit the earth and all of them are subject to aging. This book is aimed at persons interested in a molecular explanation of how our cells age. Human Longevity: Omega-3 Fatty Acids, Bioenergetics, Molecular Biology, and Evolution is built on the proposition that we age as our mitochondria age. It suggests a revised version of Harman’s famous hypothesis featuring mitochondrial oxidative and energy stresses as the root causes of aging.

Human cells are protected from the ravages of aging by a battery of defensive systems including some novel mechanisms against membrane oxidation introduced in this book. This concept is consistent with recent discoveries showing that mitochondria-targeted antioxidants prevent Huntington’s disease, Parkinson’s disease, and traumatic brain disease in animal models of neurodegeneration.

This book explores a unified theory of aging based on bioenergetics. It covers a variety of topics including an introduction to the science of human aging, the Darwinian selection of membranes enabling longevity, a revised mitochondrial membrane hypothesis of aging, and various mechanisms that protect human mitochondrial membranes, thereby enabling longevity.

Book details

Book category Books in English Medicine Pre-clinical medicine: basic sciences Physiology

• Full title: Human Longevity
• Author: David L. Valentine
• Language: English
• Binding: Hardback
• Number of pages: 259
• EAN: 9781466594869
• ISBN: 9781466594869
• ID: 06696058
• Publisher: Taylor & Francis Inc
• Weight: 496 g
• Dimensions: 163 × 236 × 19 mm
• Date of publishing: 18. September 2014

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