Kód: 37072502
Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. Aptamers possess excellent specificity and ... celý popis
Nákupom získate 868 bodov
Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. Aptamers possess excellent specificity and high affinity to targets; when conjugated with functional nanomaterials, the specific binding ability and specialized properties of these nano-aptamers to cancer-related markers and cancer cells, may lead to early diagnosis of cancer and a better patient outlook. This book helps facilitate speedy solutions to some of the problems pertaining to the manufacture of nano-aptamers – such as toxicity, thermal stability, cost efficiency, tumour penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection; mechanisms of multi-drug resistance of cancer and the relevance of aptamers as anticancer therapies, as well as detailing the broad range of aptamer-functionalized nanostructures available. Aptamers Engineered Nanocarriers for Cancer Therapy provides an exciting insight into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists with a focus on cancer therapy. Reviews the mechanisms behind mutli-drug resistance (MDR) of cancer, and how aptamer-mediated novel therapeutic agents and strategies can facilitate MDR reversal Covers a range of aptamers engineered nanostructures, including PLGA nanoparticles, silica nanoparticles, quantum dots, nucleic acid aptamers and more Discusses the challenges associated with using aptamers as cancer therapeutics, and how this translates in clinical use
Zaradenie knihy Knihy po anglicky Medicine Nursing & ancillary services Biomedical engineering
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