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Viac informácií o knihe Computational Methods for GPCR Drug Discovery

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• Anotácia kniha
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Nákupom získate 365 bodov

Anotácia knihy

This volume looks at modern computational strategies and techniques used in GPCR drug discovery including structure and ligand-based approaches and cheminformatics. The chapters in this book describe how these approaches can be applied to address key drug discovery issues, such as receptor structure modelling, function and dynamics, prediction of protein-water-ligand interactions and binding kinetics, free energy of binding, interconversion between agonists and antagonists, deorphanization of GPCRs, and the discovery of biased and allosteric modulators. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modelling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Computational Methods for GPCR Drug Discovery is a valuable resource for struc tural and molecular biologists, computational and medicinal chemists, pharmacologists, and drug designers

Parametre knihy

Zaradenie knihy Knihy po anglicky Medicine Other branches of medicine Pharmacology

• Celý názov: Computational Methods for GPCR Drug Discovery
• Autor: Alexander Heifetz
• Jazyk: Angličtina
• Väzba: Pevná
• Počet strán: 436
• EAN: 9781493974641
• ISBN: 1493974645
• ID: 17768158
• Nakladateľ: Humana Press Inc.
• Hmotnosť: 9806 g
• Rozmery: 254 × 178 × 28 mm
• Dátum vydania: 30. November 2017

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