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Book synopsis

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist's approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound's physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facets and detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

Book details

• Full title: Formulating Poorly Water Soluble Drugs
• Author: Robert O. III Williams, Daniel A. Davis Jr., Dave A. Miller
• Language: English
• Binding: Paperback
• Number of pages: 693
• EAN: 9783030887216
• ID: 43312447
• Publisher: Springer, Berlin
• Dimensions: 254 × 178 mm
• Date of publishing: 03. June 2023

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