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Viac informácií o knihe Long-lasting stress-induced changes in neuronal alternative splicing

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Ample information suggests multileveled relationships§between long-term psychological stress responses and§alternative splicing the process which yields§different mRNAs from the same gene. However, the§nature of these relationships remains unclear. Eran§Meshorer studied the stress-induced changes in§alternative splicing at Hermona Soreq s lab and shed§light on the molecular pathways that lead to such§responses. Meshorer focused on a particular mRNA -§acetylcholinesterase (AChE), which is§neuronally-expressed, stress-responsive, and yields§alternatively spliced products, thus serving as an§adequate model for this purpose. The book begins with§an introduction covering the general areas of stress§responses, their long-term consequences, the§mechanism of splicing and alternative splicing,§neuritic translocation of mRNAs and highlights the§AChE gene and its protein products as putative§mediators of such long-term consequences. The results§section depicts 3 works describing 3 and 5 §alternative splicing of AChE and a potential mediator§of the stress-induced responses. Finally, the book§ends with a discussion on the consequences of such§responses, linking stress responses with aging.

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Zaradenie knihy Knihy po anglicky Mathematics & science Biology, life sciences

• Celý názov: Long-lasting stress-induced changes in neuronal alternative splicing
• Autor: Eran Meshorer
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 100
• EAN: 9783639147162
• ISBN: 3639147162
• ID: 06823290
• Nakladateľ: VDM Verlag
• Hmotnosť: 159 g
• Rozmery: 229 × 152 × 6 mm
• Dátum vydania: 17. April 2009

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