Mohlo by sa vám tiež páčiť

Viac informácií o knihe Molecular Dissection of the Clonal M1T1 Group A Streptococci

• Parametre knihy
• Anotácia kniha
• Obľúbené z iného súdka

Nákupom získate 217 bodov

Anotácia knihy

A particular strain of the group A streptococci (GAS), known as the M1T1 clone, has exhibited unusual epidemiology and virulence, and has been largely associated with the pandemic of invasive GAS infections worldwide. M1T1 was among few GAS strains that have outnumbered other serotypes since the mid-1980s, and their increase in GAS populations coincided with the resurgence of invasive and severe forms of streptococcal diseases, especially the streptococcal toxic shock syndrome (STSS) and necrotizing fasciitis (NF). The resurgence of the severe diseases was thus suspected to be a result of an unusual pathogenic potential inherent to the few reemerging strains. This book, based on my PhD dissertation, discusses unique features that may have endowed the global M1T1 clone with its unusual properties, and the genomic and evolutionary basis for its emergence and persistence. Among M1T1''s unique features are its ability to switch to a hypervirulent phenotype with a survival advantage in deep tissues; the acquisition and exchange of mosaic prophages that encode novel exotoxins; and the production of the potent DNase Sda1, which frees the bacteria from the leukocyte extracellular traps.

Parametre knihy

Zaradenie knihy Knihy po anglicky Mathematics & science Biology, life sciences Microbiology (non-medical)

• Celý názov: Molecular Dissection of the Clonal M1T1 Group A Streptococci
• Autor: Ramy Karam Aziz
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 164
• EAN: 9783639196597
• ISBN: 3639196597
• ID: 06827727
• Nakladateľ: VDM Verlag
• Hmotnosť: 249 g
• Rozmery: 229 × 152 × 10 mm
• Dátum vydania: 09. October 2009

Obľúbené z iného súdka

---

---

---