Mohlo by sa vám tiež páčiť

Viac informácií o knihe Murine Interferon Regulatory Factor-2 (IRF-2) and Escherichia coli

• Parametre knihy
• Anotácia kniha
• Obľúbené z iného súdka

Nákupom získate 160 bodov

Anotácia knihy

Interferon Regulatory Factor-2 is a vertebrate transcription factor having oncogenic nature; it antagonises Interferon Regulatory Factor-1, a tumor suppressor gene, functions. Knockout mice for IRF-2 gene showed defect in B-cell lymphopoeisis, they died following LCMV (Lymphocytic Choriomeningitis Virus) infections. IRF-2 is functionally just opposite of IRF-1. Interestingly, one would have thought that as IRF-1-/- (knock-out) mice showed lack of CD8+T cells and low cytotoxicity of NK cells, the over production of IRF-2 in mice may restore it. But it does not happen so, the reason being unknown. However, IRF-2 binds at Interferon Stimulated Response Element sequence in viral infected cell. This book is about mouse IRF-2 gene cDNA cloning and expression of chimeric protein in E.coli. This study will serve as a platform for further functional analysis of chimeric IRF-2, which is potent oncogene in aberrant conditions.

Parametre knihy

• Celý názov: Murine Interferon Regulatory Factor-2 (IRF-2) and Escherichia coli
• Autor: Krishna Prakash, Ajeet Kumar
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 116
• EAN: 9786139861019
• ID: 19747672
• Nakladateľ: Lambert Academic Publishing
• Hmotnosť: 181 g
• Rozmery: 229 × 152 × 7 mm
• Dátum vydania: 20. June 2018

Obľúbené z iného súdka

---

---

---