Kód: 01400753
A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds, turn mimetics, peptide-bound replacements, and enzyme inhibitors. Topics range from unusual syntheses of amino acids to the use of ... celý popis
Angličtina
103.10 €
Bežne: 111.73 €
Ušetríte 8.64 €

Nákupom získate 249 bodov
Anotácia knihy
A state-of-the-art collection of detailed synthetic procedures that lead to a variety of scaffolds, turn mimetics, peptide-bound replacements, and enzyme inhibitors. Topics range from unusual syntheses of amino acids to the use of a variety of linear and heterocyclic scaffolds in place of the peptide backbone. Important chemical procedures and methods include the transient protection of charged peptides as neutral prodrugs for improved blood-brain penetration and the replacement of peptide bonds with heterocyclic rings, olefins and fluoroolefins, and ketomethylenes. Synthetic protocols towards the transition-state mimics and reactive "warheads," applicable in enzyme inhibitors, are also disclosed.
Parametre knihy
Zaradenie knihy Knihy po anglicky Medicine Other branches of medicine Pharmacology
103.10 €
Angličtina
Osobný odber Bratislava a 12840 dalších
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