You might also like

More about Statistical Methods for CGH Array Analysis

• Book details
• Synopsis
• Trending among others

You get 121 loyalty points

Book synopsis

Genomic DNA copy number alterations are key genetic events in the initiation and progression of human cancers. Recent advance in the technique of microarray comparative genomic hybridization (array CGH) enables one to screen genome-wide for all possible regions with DNA copy number alterations, such as chromosome gains and losses, or localized amplifications and deletions. In this book, we introduce two statistical methods addressing two different questions for the data analysis of array CGH. The first method---Cluster Along Chromosomes--- is developed for calling gains and losses in CGH arrays. The second method--- Boosted PRIM (Patient Rule Induction Method)--- is developed to search for oncogenic pathways using array-CGH data. The performance of the methods are illustrated through both simulation studies and real applications.

Book details

Book category Knihy po anglicky Mathematics & science Mathematics Probability & statistics

• Full title: Statistical Methods for CGH Array Analysis
• Author: Pei Wang
• Language: English
• Binding: Paperback
• Number of pages: 38
• EAN: 9783639114065
• ISBN: 363911406X
• ID: 06820282
• Publisher: VDM Verlag
• Weight: 68 g
• Dimensions: 229 × 152 × 2 mm
• Date of publishing: 26. February 2010

Trending among others

---

---

---