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Book synopsis

Membrane transporters can be major determinants of the pharmacokinetic, safety and efficacy profiles of drugs. This presents several key questions for drug development, including which transporters are clinically important in drug absorption and disposition, and which in vitro methods are suitable for studying drug interactions with these transporters. In addition, what criteria should trigger follow-up clinical studies, and which clinical studies should be conducted if needed. This book, written by leaders in the field, will consider the key elements in these areas , covering both pharma industry and FDA perspectives.

Book details

Book category Knihy po anglicky Medicine Medicine: general issues Medical equipment & techniques

• Full title: Transporters in Drug Development
• Subtitle: Discovery, Optimization, Clinical Study and Regulation
• Author: Yuichi Sugiyama, Bente Steffansen
• Language: English
• Binding: Hardback
• Number of pages: 317
• EAN: 9781461482284
• ISBN: 1461482283
• ID: 01429044
• Publisher: Springer-Verlag New York Inc.
• Weight: 6878 g
• Dimensions: 235 × 155 × 18 mm
• Date of publishing: 17. September 2013

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