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Book synopsis

The objective of this work was to evaluate the §suitability of in situ forming biodegradable §microparticles for the controlled delivery of §proteins. Particular goals were: a) to evaluate the §flexibility of the release patterns of in situ §implant and in situ microparticle formulations using §hen egg white lysozyme as model protein; b) to §characterize, if and how the integrity of the model §protein is affected by formulation ingredients, the §manufacturing process, storage of the ISM and the §release from the formulations; c) to optimize §protein delivery from in situ forming implant and §microparticle systems, with regard to shape and §completeness of the release; d) to find / validate §reliable methods allowing to extract and thus to §characterize the model protein in biodegradable in §situ formulations.

Book details

Book category Knihy po anglicky Medicine Nursing & ancillary services Pharmacy / dispensing

• Full title: Biodegradable in Situ Microparticles for Sustained Protein Delivery
• Subtitle: Stability of a Model Protein during Incorporation and Release from Biodegradable in Situ Forming Drug Delivery Systems
• Author: Martin Körber
• Language: English
• Binding: Paperback
• Number of pages: 332
• EAN: 9783639076592
• ISBN: 3639076591
• ID: 06816902
• Publisher: VDM Verlag Dr. Mueller E.K.
• Weight: 445 g
• Dimensions: 229 × 152 × 18 mm
• Date of publishing: 22. August 2008

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