Mohlo by sa vám tiež páčiť

Viac informácií o knihe CD-Mpr

• Parametre knihy
• Anotácia kniha
• Obľúbené z iného súdka

Nákupom získate 151 bodov

Anotácia knihy

The trafficking of membrane proteins between cellular compartments is regulated by their cytoplasmic signal sequences that are recognised by adaptor proteins. Adaptor proteins recruit membrane proteins into vesicles that traffic to a specific target organelle. The cation-dependent mannose 6-phosphate receptor (CD-MPR) is a membrane receptor that transports newly synthesised lysosomal enzymes from the trans-Golgi network to the lysosome and is continuously recycled. This work focused on two sorting signals that regulate the intracellular trafficking of the CD-MPR at different cellular locations. Palmitoylation is a post-translational modification that prevents missorting of the CD-MPR to lysosomes. GGA1 and AP-1 adaptor proteins bind to the cytoplasmic tail of the CD-MPR at a signal that overlaps with a phosphorylation site. This dissertation reveals novel aspects of these sorting signals and CD-MPR trafficking.

Parametre knihy

Zaradenie knihy Knihy po anglicky Mathematics & science Biology, life sciences

• Celý názov: CD-Mpr
• Podnázov: Quo Vadis?
• Autor: Jacqueline Stöckli
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 148
• EAN: 9783838129563
• ISBN: 3838129563
• ID: 07094446
• Nakladateľ: Sudwestdeutscher Verlag Fur Hochschulschriften AG
• Hmotnosť: 227 g
• Rozmery: 229 × 152 × 9 mm
• Dátum vydania: 08. November 2011

Obľúbené z iného súdka

---

---

---