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Viac informácií o knihe Formulation and Evaluation of an In Situ Gel for Ocular Delivery

• Parametre knihy
• Anotácia kniha
• Obľúbené z iného súdka

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Anotácia knihy

Norfloxacin ophthalmic solution has been shown to be effective ocular infections and may be used in patients with chronic conjunctivitis or ocular irritation. Norfloxacin in-situ gel was prepared using various concentrations of polymers such as Carbopol-940 (0., 0.2, 0.3 0.4and 0.5% w/v), HPMC- E50LV (1.5 % w/v), HPMC E4M (0.6 %w/v) and HPMC K4M (0.5% w/v) by pH triggered gelling system with an objectives of increasing contact time, achieving controlled release, reduction in frequency of administration and greater therapeutic efficacy of drug. The prepared in-situ gels were then evaluated for their visual appearance, clarity, pH, drug content analysis, in-vitro gelation (Gelling capacity), rheological studies, sterility testing, textureanalysis and in-vitro drug release studies. It is evident from these studies that, formed polymeric in-situ gels had transparent, clear possessing satisfactory gelling capacity. The developed formulation was light yellow in colour, therapeutically efficacious, stable, non irritant with sustained release of drug.

Parametre knihy

• Celý názov: Formulation and Evaluation of an In Situ Gel for Ocular Delivery
• Autor: Sachinkumar Patil, Shitalkumar Patil, Amit Jagdale
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 100
• EAN: 9783659461910
• ID: 02201789
• Nakladateľ: LAP Lambert Academic Publishing
• Hmotnosť: 167 g
• Rozmery: 220 × 150 × 6 mm
• Dátum vydania: 22. October 2013

Obľúbené z iného súdka

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