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Viac informácií o knihe Genome Integrity

• Parametre knihy
• Anotácia kniha
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Nákupom získate 783 bodov

Anotácia knihy

This is the first book to give a full overview on genome integrity in different species. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. Written by an international panel of experts, the book addresses the connection between genome integrity and human disease.Cells and viruses maintain a genome capable of multiplication, variation and heredity. A genome consists of chromosomes, each being built up of two complementary strands of nucleic acid known as DNA. Its chemical integrity, however, is under constant assault from metabolic mutagens, such as hydroxy-radicals, endonucleases, radiation, replication errors, and environmental mutagens. From microorganisms to humans, this volume provides an interdisciplinary overview of how genome integrity is maintained. The volume begins with DNA replication and continues with replicative DNA repair and pleiotropic protein interactions. Examples of human diseases are included and the cellular responses to radiation and genotoxic stress affecting whole genomes are reviewed.

Parametre knihy

Zaradenie knihy Knihy po anglicky Medicine Pre-clinical medicine: basic sciences Medical genetics

• Celý názov: Genome Integrity
• Podnázov: Facets and Perspectives
• Autor: Dirk-Henner Lankenau
• Jazyk: Angličtina
• Väzba: Brožovaná
• Počet strán: 496
• EAN: 9783642072260
• ISBN: 3642072267
• ID: 01652390
• Nakladateľ: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
• Hmotnosť: 752 g
• Rozmery: 159 × 233 × 30 mm
• Dátum vydania: 24. November 2010

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