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Viac informácií o knihe Serotonin Receptors

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Nákupom získate 603 bodov

Anotácia knihy

The recent cloning and identification of a large number of serotonin (5-HT) receptors-a major family of therapeutic targets-holds out the possibility of developing novel, subtype-selective 5-HT receptor agonists and antagonists for use as psychiatric, cardiovascular, and neurological medications. In The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics, leading experts comprehensively examine our current understanding of the molecular and structural biology of 5-HT receptors and their pharmacological use. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.§Comprehensive and state of the art, The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics provides an illuminating "snapshot" of the 5-HT receptor field today and prospects for the future, taking it from the genomic to a systems level of understanding.

Parametre knihy

Zaradenie knihy Knihy po anglicky Medicine Clinical & internal medicine Neurology & clinical neurophysiology

• Celý názov: Serotonin Receptors
• Podnázov: From Molecular Pharmacology to Human Therapeutics
• Autor: Bryan L. Roth
• Jazyk: Angličtina
• Väzba: Pevná
• Počet strán: 618
• EAN: 9781588295682
• ISBN: 1588295680
• ID: 01430507
• Nakladateľ: Humana Press Inc.
• Hmotnosť: 999 g
• Rozmery: 229 × 152 × 44 mm
• Dátum vydania: 01. June 2006

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