Kód: 14115278
This book describes the phytochemical investigations carried out on two indigenous medicinal plants of Pakistan namely, Isatis costata and Leucas urticifolia. Part A is about the isolation and structure elucidation of five new alk ... celý popis
Nákupom získate 171 bodov
This book describes the phytochemical investigations carried out on two indigenous medicinal plants of Pakistan namely, Isatis costata and Leucas urticifolia. Part A is about the isolation and structure elucidation of five new alkaloids named as costinone A, costinone B, isatinone A, isatinone B and isamide. In addition, five known compounds caffeic acid ester, docosyl caffeate, methyl-2 acetoamidobenzoate, -sitosterol and ursolic acid have also been isolated and characterized for the first time from this species. Compounds costinone A and costinone B inhibited lipoxygenase and butyrylcholinesterase enzymes non-competitively in concentration-dependent fashion with promising inhibitory potentials. Compounds isatinone A and isatinone B showed vital antifungal activity. Part B describes the isolation and structure elucidation of two new compounds named as leucisterol and urticic acid, along with four known compounds named as 2-methoxybenzyl benzoate , 4-hydroxy benzoic acid , -sitosterol and ursolic acid which are reported first time from this species. The compound leucisterol showed potent inhibitory activity against butyrylcholinesterase enzyme.
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